Bridging the Internet of Things and Personalized Medicine:
An Ecosystem of Integrated Physiological and Environmental Monitoring Platforms
At Interconnected & Integrated Bioelectronics Lab (I²BL), we design and fabricate nano/microelectromechanical systems (N/MEMS)-based devices that provide actuation and sensing capabilities to control, isolate and sense biomarkers in highly complex biological media. Informative biomarkers include electrolytes, metabolites, proteins, genes and cells, the abundance of which in physiological samples such as blood, sweat, saliva and urine are indicative of the individual’s health. Additionally, we integrate our devices into electronic platforms with system-level functionalities to enable translational applications. In that regard, we exploit emerging technologies such as 3D printing and flexible, stretchable and dissolvable electronics to tailor our platforms toward the physiological sample under analysis. By creating a network of these biomonitoring platforms we can gain a comprehensive view of an individual’s health state at molecular levels. This network provides an infrastructure for the collection of large data sets at population levels, which will inform clinical investigations and generate predictive algorithms for understanding our personal and societal health needs.
(Adv. Mat. Tech. 2016)
(Lab on a Chip 2012)
(IEEE Sensors 2015)
(Lab on a Chip 2014)